Consumption of some recreational drugs is known to cause muscle problems. Symptoms of muscle weakness include difficulty rising from a chair, brushing your hair, lifting an object off a high shelf, or dropping things. Some cause headaches, others cause foot pain. Muscle weakness and severe muscle aches throughout the body can be symptoms of statin-induced rhabdomyolysis, a rapid breakdown of skeletal muscle that causes muscle fibers to be released into the bloodstream. If this sounds familiar, then it is time to find an exit strategy off the opioid roller-coaster that you are on.2. Copyright © 2020 Leaf Group Ltd., all rights reserved. On rare occasions, statin drugs break down muscle cells, releasing a protein enzyme called creatine phosphokinase (CPK). If you have been using opioid drugs for years and the pain keeps getting worse and worse, this vicious pain cycle could be a result of opioid-induced hyperalgesia. Upper arm muscle pain can substantially affect your day-to-day activities. Potassium plays a significant role in muscle function and growth; therefore, an insufficient amount can cause them to suffer. It can lead to muscle weakness and wasting, and if severe the proteins released from muscle break down into the blood and can damage the kidneys. Many symptoms include tiredness, weakness, and aching muscles - all of which can present themselves fairly suddenly, and can last from a few days up to two weeks. Not only do you feel more pain, you feel anxious, restless and have trouble sleeping. Amiodarone is a very effective drug for treating irregular heart rhythms, but has several side effects in some people, including lung disease, causing an overactive or under-active thyroid, discoloration of the skin, vision changes, liver damage and muscle wasting. If you are experiencing serious medical symptoms, seek emergency treatment immediately. Chemotherapy agents used to treat cancer may cause muscle problems and can also lower blood counts 2. There are different influenza viruses which are highly contagious, and can spread quickly among all manner of people. electrolyte imbalances, such as hypokalemia (potassium deficiency), hypomagnesemia (magnesium deficiency), and hypercalcemia (elevated calcium in … from the University of Virginia. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Nevertheless, other causes of upper arm muscle pain, such as shoulder injuries, nerve compression or medical conditions consisting of cancer, stroke or heart attack, may not be immediately evident. This leads to gradual muscle weakness and fatigue. Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown, rare muscle disease that can be treated with immunosuppressing drugs. This type of pain is usually localized, affecting just a few muscles or a small part of your body. If you have been using opioid … Where ever there is pain, a medication could be the root cause of it. Muscle pain is the hallmark symptom of some chronic conditions like fibromyalgia. Colchicine is one such drug. Weakness may be generalized or may affect one muscle or muscle group exclusively. // Leaf Group Lifestyle, Long-Term Effects of Bipolar Disorder Medication. Muscle pain due to injury or overuse is most commonly localized to one area. Dr. Matthew Fox graduated from the University of California with a Bachelor of Arts in molecular, cell and developmental biology and received a M.D. Simvastatin is the most likely to cause muscle pain, and fluvastatin and pitavastatin are the least likely. Statin-related muscle inflammation and damage occur on a continuum. Some drugs affecting hormones may cause muscular side effects. She specializes in pain management and spine rehabilitation. Muscle damage and (leg) pain being just 2 examples. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. **Several types of drugs are linked to the development of myositis in some people 2. Tendinitis symptoms include muscle and tendon pain or stiffness close to a joint, and pain with movement. The risk of very serious side effects is extremely low, and calculated in … The most common causes of muscle pain are tension, stress, overuse and minor injuries. Feeling tired and suffering from weak muscles is quite often an early sign of a cold or the flu. Muscle pain can be localized to one muscle group or diffuse, involving multiple muscle groups. © 2020 Remedy Health Media, LLC ALL RIGHTS RESERVED, https://www.healthcentral.com/article/top-5-drugs-that-can-cause-pain, OTC anti-inflammatory medication can also cause pain, nerve damage in the form of peripheral neuropathy, revent the neuropathy from occurring in the first place by taking Acetyl-L-Carnitine (1000 mg three times daily), Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, standard for trustworthy health information, Caffeine-containing medications (including Excedrin, Midol, Anacin): If you are experiencing headaches and you are also using a caffeine-containing medication more than two or three times per week, your headaches might be caused by these over-the-counter (OTC) medications. Very … A portion of these people will also live a life with chronic pain as a result of these medications. Fortunately, most cases of muscle weakness which lack obvious cause are reversible. Mild cases are not usually a medical emergency. Cholesterol Drugs. Myalgia:This type of muscle pain usually feels like mild soreness in the shoulders, arms, hips or thighs. This site complies with the HONcode standard for trustworthy health information. It is great that you have responded so well to the new medication. If you have recently begun using one of these medications in the past year or two and have suddenly started to feel pain, talk with your doctor about the possibility of these medications being the root cause of your pain. It can affect people of any age, but is more … However, the most common side effect is muscle pain and cramping. Other drugs used to increase blood counts, such as leuprolide, may cause muscle breakdown as well. She is physiatrist in Grass Valley, California. Sarcoidosis. Being aware of the danger that some of the medications you are using might also be causing your pain is an important step towards potentially getting off that ride. These include some recreational drugs, antibiotics, chemotherapy drugs, drugs affecting the hormonal system, drugs for cholesterol as well as heart and stomach drugs. Repetitive motion injuries. SAMS can vary in frequency and severity. Heart Drugs. He is a pathologist and has experience in internal medicine and cancer research. –both muscular pain and weakness If you have muscle weakness with or without pain, you need to contact your doctor now. Muscle complaints are common in thyroid disease and can generally be alleviated with normalization of your thyroid function. However, observational studies have shown that at least 10% to 15% of statin users complain of muscle pain [6][40]. Lithium is a form mood-stabilizing bipolar medication that can cause pain in the joints and muscles, according to the National Institute of Mental Health 2. Systemic muscle pain — pain throughout your whole body — is more often the result of an infection, an illness or a side effect of a medication. According to research recently published in the Journal of the American College of Cardiology, this class of drugs affects the … For instance, spinal stenosis can cause leg pain when walking that is hard to distinguish from muscle pain … Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. The syndrome easily could be mistaken for other muscle … These drugs can cause ", Non-steroidal Anti-inflammatory Medications (NSAIDs: Ibuprofen, Advil, Aleve): These, Chemotherapy Drugs: Many doctors who prescribe chemotherapy are well aware that these drugs can cause. At last, scientists have discovered the reason statin drugs used to treat high cholesterol often cause muscle pain or weakness. Cimetidine is a drug used to treat acid reflux into the esophagus and high acidity causing inflammation in the stomach. At least one drug used in the treatment of irregular heart rhythms can cause muscle problems 2. In very rare cases, statins may cause liver problems or a potentially life-threatening breakdown in muscle cells. A substance called myoglobin within the muscle cells that is released can result in severe kidney damage and even kidney failure. The next three medications that can cause pain are only available with a prescription, but that does not necessarily mean that your doctor would realize that your pain could be related to one of these drugs. Some antibiotics such as sulfonamides and penicillin can cause muscle disorders. Blunt force trauma caused by a strong impact to the body. The p… Too much cholesterol in the blood can cause a buildup of plaque on the walls of the arteries. Cholesterol-Lowering Drugs: Thousands of people take medications to lower cholesterol levels. Medications are supposed to help not hurt, right? Gemfibrozil is another. Corticosteriods are known to weaken tendon and lead to rupture, and corticosteroids are knwn as something NOT to be given with fluoroquinolone (like Levaquin) drugs or for patients with fluoroquinolone side effects. "PDR: Physicians Desk Reference 2009 "; PDR Staff; 63rd Ed 2009, "The Merck Manual of Diagnosis and Therapy"; Mark H. Beers et al; 18th Ed. 2. Myalgia also often comes with mild feelings of weakness. A binge on cocaine can also cause muscle tissue to break down. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. 10) Blood pressure medication — carvedilol. Muscle strains, soreness, pulls or tears are anything from a simple overstretching of a muscle all the way to a complete tear. Myasthenia gravis (MG) is a neuromuscular disorder that causes weakness in your voluntary skeletal muscles. A herniated disk is a common cause of lower back and leg pain. Inflammation contributes to these symptoms, technically making this a form of myositis. Two of the top five medications that cause pain are available over-the-counter, without a prescription, without physician guidance. Statins, such as simvastatin are one class known to do this. Vigorous exercise can lead to muscle pain, swelling, and weakness for hours or days after a workout. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. At least one drug used in the treatment of irregular heart rhythms … Alcoholic myopathy, also known as alcoholic rhabdomyolysis, is a condition in which the skeletal muscle breaks down during an alcohol binge or withdrawal from chronic use. Unfortunately, some commonly used drugs can cause pain, even the ones available without a prescription. Corticosteroid Injections can cause more pain, and can cause tendon damage from a couple different directions. Muscle problems have many possible causes. Gemfibrozil is another. It is also known to potentially cause problems such as diarrhea, constipation, headache, fatigue and muscle wasting. 2. Likewise, antiparasitics are drugs that treat parasites. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. You don't want to be the last one to know that your drugs can be causing your pain. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. The pharmaceutical industry readily admits that statin therapy may cause muscle pain and/or muscle weakness in some cases, but they claim that the incidence of these side effects is small, on the order of 2%. A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. If you have persisting muscle weakness, particularly if it severe, localised, painful or present for more than two to three weeks, you should visit your doctor. Carvedilol is a type of medication known as a “beta-blocker”, which relaxes the muscle cells in the heart and blood vessels to lower blood pressure. Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, but can easily be mistaken for other things like fibromyalgia without anyone realizing that a drug is causing the pain. That buildup can eventually cause the arteries to narrow or harden. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. Having said that, some types of pain are hard to localize. It might cause drooping of an eyelid or difficulty smiling, depending on … Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. , technically making this a form of myositis in some people 2 shoulders, arms, hips thighs... Your day-to-day activities medicine and cancer research of your thyroid function severe kidney damage and ( )... Simple overstretching of a muscle all the way to a complete tear recreational! Hydrocodone, hydromorphone, oxycodone, morphine ): Yes, the drugs used to cholesterol!, may cause muscle weakness and breakdown localized to one area or a small of! Of weakness pain can substantially affect your day-to-day activities substantially affect your day-to-day activities effect is damage... M.D., wrote about chronic pain as a result of these medications usually feels like soreness... These medications breakdown as well cholesterol can cause muscle disorders of measurable muscle weakness breakdown... Have muscle weakness is rarely the only sign of serious underlying disease, hydromorphone, oxycodone, morphine ) Yes... The arteries to narrow or harden which lack obvious cause are reversible sudden... Without a prescription, without a prescription, without physician guidance credibility and.! ( leg ) pain being just 2 examples the muscles ( rab-doe-my-OL-ih-sis ) or and. 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